Daily Papers

The rapid growth of biomedical data, tools, and literature has created a fragmented research landscape that outpaces human expertise. While AI agents offer a solution, they typically rely on static, manually curated toolsets, limiting their ability to adapt and scale. Here, we introduce STELLA, a self-evolving AI agent designed to overcome these limitations. STELLA employs a multi-agent architecture that autonomously improves its own capabilities through two core mechanisms: an evolving Template Library for reasoning strategies and a dynamic Tool Ocean that expands as a Tool Creation Agent automatically discovers and integrates new bioinformatics tools. This allows STELLA to learn from experience. We demonstrate that STELLA achieves state-of-the-art accuracy on a suite of biomedical benchmarks, scoring approximately 26\% on Humanity's Last Exam: Biomedicine, 54\% on LAB-Bench: DBQA, and 63\% on LAB-Bench: LitQA, outperforming leading models by up to 6 percentage points. More importantly, we show that its performance systematically improves with experience; for instance, its accuracy on the Humanity's Last Exam benchmark almost doubles with increased trials. STELLA represents a significant advance towards AI Agent systems that can learn and grow, dynamically scaling their expertise to accelerate the pace of biomedical discovery.

Rapid Large Language Model (LLM) advancements are fueling autonomous Multi-Agent System (MAS) development. However, current frameworks often lack flexibility, resource awareness, model diversity, and autonomous tool creation. This paper introduces HASHIRU (Hierarchical Agent System for Hybrid Intelligent Resource Utilization), a novel MAS framework enhancing flexibility, resource efficiency, and adaptability. HASHIRU features a "CEO" agent dynamically managing specialized "employee" agents, instantiated based on task needs and resource constraints (cost, memory). Its hybrid intelligence prioritizes smaller, local LLMs (via Ollama) while flexibly using external APIs and larger models when necessary. An economic model with hiring/firing costs promotes team stability and efficient resource allocation. The system also includes autonomous API tool creation and a memory function. Evaluations on tasks like academic paper review (58% success), safety assessments (100% on a JailbreakBench subset), and complex reasoning (outperforming Gemini 2.0 Flash on GSM8K: 96% vs. 61%; JEEBench: 80% vs. 68.3%; SVAMP: 92% vs. 84%) demonstrate HASHIRU's capabilities. Case studies illustrate its self-improvement via autonomous cost model generation, tool integration, and budget management. HASHIRU offers a promising approach for more robust, efficient, and adaptable MAS through dynamic hierarchical control, resource-aware hybrid intelligence, and autonomous functional extension. Source code and benchmarks are available at https://github.com/HASHIRU-AI/HASHIRU and https://github.com/HASHIRU-AI/HASHIRUBench respectively, and a live demo is available at https://hashiruagentx-hashiruai.hf.space upon request.

This technical brief introduces Deep Agent, an advanced autonomous AI system designed to manage complex multi-phase tasks through a novel hierarchical task management architecture. The system's foundation is built on our Hierarchical Task DAG (HTDAG) framework, which dynamically decomposes high-level objectives into manageable sub-tasks while rigorously maintaining dependencies and execution coherence. Deep Agent advances beyond traditional agent systems through three key innovations: First, it implements a recursive two-stage planner-executor architecture that enables continuous task refinement and adaptation as circumstances change. Second, it features an Autonomous API & Tool Creation (AATC) system that automatically generates reusable components from UI interactions, substantially reducing operational costs for similar tasks. Third, it incorporates Prompt Tweaking Engine and Autonomous Prompt Feedback Learning components that optimize Large Language Model prompts for specific scenarios, enhancing both inference accuracy and operational stability. These components are integrated to form a service infrastructure that manages user contexts, handles complex task dependencies, and orchestrates end-to-end agentic workflow execution. Through this sophisticated architecture, Deep Agent establishes a novel paradigm in self-governing AI systems, demonstrating robust capability to independently handle intricate, multi-step tasks while maintaining consistent efficiency and reliability through continuous self-optimization.

Recent advances in agent systems have demonstrated remarkable capabilities in solving both general-purpose and highly complex tasks. However, most current models lack mechanisms for coordinating specialized agents and have limited ability to generalize to new or diverse domains. To this end, we introduce AgentOrchestra, a hierarchical multi-agent framework for general-purpose task solving that integrates high-level planning with modular agent collaboration. Drawing inspiration from a conductor orchestrating a symphony, and grounded in the principles of extensibility, multimodality, modularity, and coordination, it features a central planning agent that decomposes complex objectives and delegates sub-tasks to a team of specialized agents. Each sub-agent is equipped with general programming tools, as well as abilities to tackle a wide range of real-world specific tasks, including data analysis, file operations, web navigation, and interactive reasoning in dynamic multimodal environments. Notably, AgentOrchestra introduces an MCP Manager Agent that enables intelligent evolution through dynamic tool creation, retrieval, and reuse mechanisms, significantly enhancing the system's adaptability and scalability. AgentOrchestra supports flexible orchestration through explicit sub-goal formulation, inter-agent communication, and adaptive role allocation. We evaluate the framework on three widely used benchmarks for assessing LLM-based agent systems. Experimental results show that AgentOrchestra consistently outperforms flat-agent and monolithic baselines in terms of task success rate and adaptability. On the GAIA benchmark testing dataset, AgentOrchestra achieves an average score of 83.39\%, ranking among the top general-purpose agents. These results highlight the effectiveness of hierarchical organization and role specialization in building scalable and general-purpose LLM-based agent systems.

Creating autonomous virtual agents capable of using arbitrary software on any digital device remains a major challenge for artificial intelligence. Two key obstacles hinder progress: insufficient infrastructure for building virtual agents in real-world environments, and the need for in-the-wild evaluation of fundamental agent abilities. To address this, we introduce AgentStudio, an online, realistic, and multimodal toolkit that covers the entire lifecycle of agent development. This includes environment setups, data collection, agent evaluation, and visualization. The observation and action spaces are highly generic, supporting both function calling and human-computer interfaces. This versatility is further enhanced by AgentStudio's graphical user interfaces, which allow efficient development of datasets and benchmarks in real-world settings. To illustrate, we introduce a visual grounding dataset and a real-world benchmark suite, both created with our graphical interfaces. Furthermore, we present several actionable insights derived from AgentStudio, e.g., general visual grounding, open-ended tool creation, learning from videos, etc. We have open-sourced the environments, datasets, benchmarks, and interfaces to promote research towards developing general virtual agents for the future.

More than a decade has passed since the development of FearNot!, an application designed to help children deal with bullying through role-playing with virtual characters. It was also the application that led to the creation of FAtiMA, an affective agent architecture for creating autonomous characters that can evoke empathic responses. In this paper, we describe FAtiMA Toolkit, a collection of open-source tools that is designed to help researchers, game developers and roboticists incorporate a computational model of emotion and decision-making in their work. The toolkit was developed with the goal of making FAtiMA more accessible, easier to incorporate into different projects and more flexible in its capabilities for human-agent interaction, based upon the experience gathered over the years across different virtual environments and human-robot interaction scenarios. As a result, this work makes several different contributions to the field of Agent-Based Architectures. More precisely, FAtiMA Toolkit's library based design allows developers to easily integrate it with other frameworks, its meta-cognitive model affords different internal reasoners and affective components and its explicit dialogue structure gives control to the author even within highly complex scenarios. To demonstrate the use of FAtiMA Toolkit, several different use cases where the toolkit was successfully applied are described and discussed.

The recent trend of using Large Language Models (LLMs) as intelligent agents in real-world applications underscores the necessity for comprehensive evaluations of their capabilities, particularly in complex scenarios involving planning, creating, and using tools. However, existing benchmarks typically focus on simple synthesized queries that do not reflect real-world complexity, thereby offering limited perspectives in evaluating tool utilization. To address this issue, we present UltraTool, a novel benchmark designed to improve and evaluate LLMs' ability in tool utilization within real-world scenarios. UltraTool focuses on the entire process of using tools - from planning and creating to applying them in complex tasks. It emphasizes real-world complexities, demanding accurate, multi-step planning for effective problem-solving. A key feature of UltraTool is its independent evaluation of planning with natural language, which happens before tool usage and simplifies the task solving by mapping out the intermediate steps. Thus, unlike previous work, it eliminates the restriction of pre-defined toolset during planning. Through extensive experiments on various LLMs, we offer novel insights into the evaluation of capabilities of LLMs in tool utilization, thereby contributing a fresh perspective to this rapidly evolving field. The benchmark is publicly available at https://github.com/JoeYing1019/UltraTool.

Recent advances on large language models (LLMs) enable researchers and developers to build autonomous language agents that can automatically solve various tasks and interact with environments, humans, and other agents using natural language interfaces. We consider language agents as a promising direction towards artificial general intelligence and release Agents, an open-source library with the goal of opening up these advances to a wider non-specialist audience. Agents is carefully engineered to support important features including planning, memory, tool usage, multi-agent communication, and fine-grained symbolic control. Agents is user-friendly as it enables non-specialists to build, customize, test, tune, and deploy state-of-the-art autonomous language agents without much coding. The library is also research-friendly as its modularized design makes it easily extensible for researchers. Agents is available at https://github.com/aiwaves-cn/agents.

SmartAvatar is a vision-language-agent-driven framework for generating fully rigged, animation-ready 3D human avatars from a single photo or textual prompt. While diffusion-based methods have made progress in general 3D object generation, they continue to struggle with precise control over human identity, body shape, and animation readiness. In contrast, SmartAvatar leverages the commonsense reasoning capabilities of large vision-language models (VLMs) in combination with off-the-shelf parametric human generators to deliver high-quality, customizable avatars. A key innovation is an autonomous verification loop, where the agent renders draft avatars, evaluates facial similarity, anatomical plausibility, and prompt alignment, and iteratively adjusts generation parameters for convergence. This interactive, AI-guided refinement process promotes fine-grained control over both facial and body features, enabling users to iteratively refine their avatars via natural-language conversations. Unlike diffusion models that rely on static pre-trained datasets and offer limited flexibility, SmartAvatar brings users into the modeling loop and ensures continuous improvement through an LLM-driven procedural generation and verification system. The generated avatars are fully rigged and support pose manipulation with consistent identity and appearance, making them suitable for downstream animation and interactive applications. Quantitative benchmarks and user studies demonstrate that SmartAvatar outperforms recent text- and image-driven avatar generation systems in terms of reconstructed mesh quality, identity fidelity, attribute accuracy, and animation readiness, making it a versatile tool for realistic, customizable avatar creation on consumer-grade hardware.

Scientific knowledge creation is fundamentally transforming as humans and AI systems evolve beyond tool-user relationships into co-evolutionary epistemic partnerships. When AlphaFold revolutionized protein structure prediction, researchers described engaging with an epistemic partner that reshaped how they conceptualized fundamental relationships. This article introduces Cognitio Emergens (CE), a framework addressing critical limitations in existing models that focus on static roles or narrow metrics while failing to capture how scientific understanding emerges through recursive human-AI interaction over time. CE integrates three components addressing these limitations: Agency Configurations describing how authority distributes between humans and AI (Directed, Contributory, Partnership), with partnerships dynamically oscillating between configurations rather than following linear progression; Epistemic Dimensions capturing six specific capabilities emerging through collaboration across Discovery, Integration, and Projection axes, creating distinctive "capability signatures" that guide development; and Partnership Dynamics identifying forces shaping how these relationships evolve, particularly the risk of epistemic alienation where researchers lose interpretive control over knowledge they formally endorse. Drawing from autopoiesis theory, social systems theory, and organizational modularity, CE reveals how knowledge co-creation emerges through continuous negotiation of roles, values, and organizational structures. By reconceptualizing human-AI scientific collaboration as fundamentally co-evolutionary, CE offers a balanced perspective that neither uncritically celebrates nor unnecessarily fears AI's evolving role, instead providing conceptual tools for cultivating partnerships that maintain meaningful human participation while enabling transformative scientific breakthroughs.